6-Aminocaproic acid
Synonyms
6-Aminohexanoic acid;
Aminocaproic acid;
Hexanoic acid, 6-amino-;
epsilon-Aminocaproic acid;
Category
Zwitterionic Surfactant
> Amino Acid Type
>> Amino acid and its Salts
Chemical Numbering System
CAS: 60-32-2
EINECS: 200-469-3
Molecular Formula & Molecular Weight
Molecular Formula: C6H13NO2; C6H13N1O2
Molecular Weight: 131.17
Structure
Properties
Appearance (1), white solid.
Solubility soluble in water.
Stability stable.
Risk Solid form: flammable material; irritation, irritation to skin, eye, respiratory system. Harmful products of combustion are CO, CO2 and so on. Contact with strong oxidants, can cause to burn.
GHS label: 
Animal Toxicity
Table 1 Animal toxicity values
|
rat oral LD |
>10000mg/kg[1] |
|
rat intraperitoneal LD50 |
7000mg/kg[1] |
|
rat intravenous LD50 |
3300mg/kg[1] |
|
mouse oral LD50 |
14300mg/kg[1] |
|
mouse intravenous LD50 |
4900mg/kg[1] |
|
mouse subcutaneous LD50 |
5790mg/kg[1] |
|
dog oral LD50 |
> 7000mg/kg[1] |
|
dog intravenous LDLo |
2150mg/kg[1] |
|
guinea pig intravenous LDLo |
19800mg/kg[1] |
|
monkey intravenous LD50 |
> 2000mg/kg[1] |
|
monkey oral LD50 |
> 7000mg/kg[1] |
|
rabbit intravenous LD50 |
2000mg/kg[1] |
Human Toxicity
Table 2 Human toxicity values
|
man oral TDLo |
1778mg/kg/8D-[1] |
|
women oral TDLo |
12600mg/kg/5W[1] |
|
women oral TDLo |
33600mg/kg/14[1] |
Ecology may be hazardous to environment. Water body should be given special attention.
Biodegradability biodegradable.
Characteristics excellent antistatic, dispersing, emulsifying abilities.
Synthesis
Quality Standards & Test Methods
1, Physical and chemical indexes
|
Item |
Physical and chemical indexes |
|
Solid |
|
|
Actives, %, ≥ |
95.0 |
Test Methods
(1), Actives
GB/T 13173 Surface active agents -- Detergents -- Testing methods
Ninhydrin method
2, Hazardous substances indexes
|
Item |
Hazardous substances indexes |
|
Solid |
|
|
Heavy metals (as Pb), mg/kg, ≤ |
20 |
|
As, mg/kg, ≤ |
3 |
Test Methods
(1), Heavy metals (as Pb)
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30799 The test method of food detergents -- Determination of heavy metals
(2), As
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30797 The test method of food detergents -- Determination of total arsenic
3, Product standards
(1), Chinese standards
(1a), Chinese Pharmacopoeia (2015 Edition) Aminocaproic acid
4, Further explanation
(a), On physical and chemical indexes: firstly, shall be indicated carbon atom distribution; secondly, shall be indicated average molecular weight.
Major Uses
1, Typical applications
Use as dispersing agent, emulsion stabilizer.
2, Medicine
Use as pharmaceutical ingredient (hemostatics). (This section is for reference only, should be implemented according to local Pharmacopoeia.)
3, Organic synthesis
Used in organic synthesis, for example, the preparation of nylon 6.
Manufacturers
References
[1]: ChemIDplus. 60-32-2, 6-Aminocaproic acid
Update: 20140913(1); 20190414(2);