Dronabinol
Synonyms
1-trans-delta9-Tetrahydrocannabinol;
6H-Dibenzo(b,d)pyran-1-ol, 6a,7,8,10a-tetrahydro-6,6,9-trimethyl-3-pentyl-, (6aR,10aR)-;
delta9-THC;
1-trans-delta-9-Tetrahydrocannabinol;
Category
Non-ionic surfactant
> Phenol
>> Ether-group Phenol
Chemical Numbering System
CAS: 1972-08-3
EINECS: N/A
Molecular Formula & Molecular Weight
Molecular Formula: C21H30O2
Molecular Weight: 314.46
Structure
Properties
Appearance (1), liquid.
Solubility insoluble in water.
Stability stable. Easily oxidized.
Risk Liquid form: flammable material; irritation, irritation to skin, eye. Harmful products of combustion are CO, CO2 and so on. Contact with strong oxidants, can cause to burn.
GHS label: 
Animal Toxicity
Table 1 Animal toxicity values
|
dog oral LDLo |
525mg/kg[1] |
|
monkey oral LD |
> 3150mg/kg[1] |
|
monkey intravenous LD50 |
125mg/kg[1] |
|
mouse intraperitoneal LD50 |
168mg/kg[1] |
|
mouse intravenous LD50 |
42mg/kg[1] |
|
mouse oral LD50 |
482mg/kg[1] |
|
mouse subcutaneous LD50 |
> 11000mg/kg[1] |
|
rat intraperitoneal LD50 |
373mg/kg[1] |
|
rat intravenous LD50 |
29mg/kg[1] |
|
rat oral LD50 |
666mg/kg[1] |
Reproductive effect.
Ecology may be hazardous to environment. Water body should be given special attention.
Biodegradability biodegradable.
Characteristics excellent antiemetic, analgesic, dispersing abilities.
Synthesis
Quality Standards & Test Methods
1, Physical and chemical indexes
|
Item |
Physical and chemical indexes |
|
Liquid |
|
|
Actives, %, ≥ |
95.0 |
Test Methods
(1), Actives
GB/T 13173 Surface active agents -- Detergents -- Testing methods
2, Hazardous substances indexes
|
Item |
Hazardous substances indexes |
|
Liquid |
|
|
Heavy metals (as Pb), mg/kg, ≤ |
20 |
|
As, mg/kg, ≤ |
3 |
Test Methods
(1), Heavy metals (as Pb)
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30799 The test method of food detergents -- Determination of heavy metals
(2), As
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30797 The test method of food detergents -- Determination of total arsenic
3, Further explanation
(a), On physical and chemical indexes: firstly, shall be indicated carbon atom distribution; secondly, shall be indicated average molecular weight.
Major Uses
1, Typical applications
Use as pharmaceutical ingredient (For reference only.).
Manufacturers
References
[1]: ChemIDplus. 1972-08-3, Dronabino
Update: 20190901(1)