Oxprenolol
Synonyms
2-Propanol, 1-((1-methylethyl)amino)-3-(2-(2-propenyloxy)phenoxy)-;
Category
Non-ionic surfactant
> Amine
>> Ether-group Amine
>>> Ether-group Chain Amine
>>>> Aryloxy Alcohol Amine
Chemical Numbering System
CAS: 6452-71-7
EINECS: 229-257-9
Molecular Formula & Molecular Weight
Molecular Formula: C15H23NO3; C15H23N1O3
Molecular Weight: 265.35
Structure
Properties
Appearance (1), solid.
Solubility slightly soluble in water.
Stability stable. Easily oxidized.
Risk Solid form: flammable material; irritation, irritation to skin, eye, respiratory system. Harmful products of combustion are CO, CO2, nitrogen oxides and so on. Contact with strong oxidants, can cause to burn.
GHS label: 
Animal Toxicity
Table 1 Animal toxicity values
|
mouse intraperitoneal LD50 |
170mg/kg[1] |
|
mouse intravenous LD50 |
20mg/kg[1] |
|
mouse oral LD50 |
375mg/kg[1] |
Human Toxicity
Table 2 Human toxicity values
|
human oral TDLo |
50mg/kg[1] |
Ecology may be hazardous to environment. Water body should be given special attention.
Biodegradability biodegradable.
Characteristics excellent anti-anxiety, anti-arrhythmia, antihypertensive, antistatic, dispersing abilities.
Synthesis
Quality Standards & Test Methods
1, Physical and chemical indexes
|
Item |
Physical and chemical indexes |
|
Solid |
|
|
Actives, %, ≥ |
95.0 |
Test Methods
(1), Actives
GB/T 13173 Surface active agents -- Detergents -- Testing methods
2, Hazardous substances indexes
|
Item |
Hazardous substances indexes |
|
Solid |
|
|
Heavy metals (as Pb), mg/kg, ≤ |
20 |
|
As, mg/kg, ≤ |
3 |
Test Methods
(1), Heavy metals (as Pb)
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30799 The test method of food detergents -- Determination of heavy metals
(2), As
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30797 The test method of food detergents -- Determination of total arsenic
3, Product standards
(1), Chinese standards
(1a), Chinese Pharmacopoeia (2020 Edition) Oxprenolol
4, Further explanation
(a), On physical and chemical indexes: firstly, shall be indicated carbon atom distribution; secondly, shall be indicated average molecular weight.
Major Uses
1, Typical applications
Use as pharmaceutical ingredient (beta-adrenergic receptor blocker). (For reference only, should be implemented according to local Pharmacopoeia.)
Manufacturers
References
[1]: ChemIDplus. 6452-71-7, Oxprenolol
Update: 20200822(1);