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Aprobarbital

Time: 2015-07-29 15:27:08; Count: 9

Aprobarbital

Synonyms

2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-(1-methylethyl)-5-(2-propenyl)-;

Barbituric acid, 5-allyl-5-isopropyl-;

Category

Non-ionic surfactant

> Amide

>> Lactams

Chemical Numbering System

CAS: 77-02-1

EINECS: 200-997-4

Molecular Formula & Molecular Weight

Molecular Formula: C10H14N2O3

Molecular Weight: 210.23

Structure

Properties

Appearance    (1), solid.

Solubility    slightly soluble in water.

Stability    stable.

Risk    Solid form: flammable material; irritation, irritation to skin, eye, respiratory system. Harmful products of combustion are CO, CO2 and so on. Contact with strong oxidants, can cause to burn.

GHS label:  

Animal Toxicity

Table 1 Animal toxicity values

mouse intraperitoneal LD50

200mg/kg[1]

mouse subcutaneous LD50

350mg/kg[1]

rabbit intraperitoneal LDLo

90mg/kg[1]

rabbit oral LDLo

160mg/kg[1]

rat intraperitoneal LDLo

100mg/kg[1]

Ecology    may be hazardous to environment. Water body should be given special attention.

Biodegradability    biodegradable.

Characteristics    excellent hypnotic, sedative, dispersing abilities.

Synthesis

 

Quality Standards & Test Methods

1, Physical and chemical indexes

Item

Physical and chemical indexes

Solid

Actives, %, ≥

95.0

Test Methods

(1), Actives

GB/T 13173 Surface active agents -- Detergents -- Testing methods

2, Hazardous substances indexes

Item

Hazardous substances indexes

Solid

Heavy metals (as Pb), mg/kg, ≤

20

As, mg/kg, ≤

3

Test Methods

(1), Heavy metals (as Pb)

Safety and Technical Standards for Cosmetics (2015 Edition)

GB/T 30799 The test method of food detergents -- Determination of heavy metals

(2), As

Safety and Technical Standards for Cosmetics (2015 Edition)

GB/T 30797 The test method of food detergents -- Determination of total arsenic

3, Further explanation

(a), On physical and chemical indexes: firstly, shall be indicated carbon atom distribution; secondly, shall be indicated average molecular weight.

Major Uses

1, Typical applications

Use as pharmaceutical ingredient (For reference only.).

Manufacturers

 

References

[1]: ChemIDplus. 77-02-1, Aprobarbital

Update: 20190818(1);

Article

[Terminology] Dispersion system

[Terminology] Vesicle

Pandect of Ester surfactants (1): Definition

[Terminology] Van Der Waals force

[Terminology] Micellar aggregation number

Standard

Test methods of surfactants, catalog, Chinese national standards

Surfactants, catalog, Chinese national standards